abstract：:The existence of primary pneumonic plague outbreaks raises concerns over the use of the causative bacteria as an aerosol-based bioweapon. We employed an individual-based model, parameterised using published personal contact information, to assess the severity of a deliberate release in a discrete community, under the ...

journal_title：Epidemics

authors： Williams AD,Hall IM,Rubin GJ,Amlôt R,Leach S

更新日期：2011-06-01 00:00:00

abstract：:The susceptibility of the English and Welsh fish farming and fisheries industry to emergent diseases is assessed using a stochastic simulation model. The model dynamics operate on a network comprising directed transport and river contacts, as well as undirected local and fomite transmissions. The directed connections ...

journal_title：Epidemics

authors： Jonkers AR,Sharkey KJ,Thrush MA,Turnbull JF,Morgan KL

更新日期：2010-12-01 00:00:00

abstract：:The classical antigen presentation pathway consists of two monomorphic (proteasome and TAP) and one polymorphic components (MHC Class I). Viruses can escape CTL responses by mutating an epitope so that it is no longer correctly processed by the pathway. Whereas escape mutations that affect MHC binding are typically no...

journal_title：Epidemics

authors： Schmid BV,Kęsmir C,de Boer RJ

更新日期：2010-09-01 00:00:00

abstract：:In late April 2009 the emergence of 2009 pandemic influenza A (H1N1pdm) virus was detected in humans. From its detection through July 18th, 2009, confirmed cases of H1N1pdm in the Americas were periodically reported to the Pan American Health Organization (PAHO) by member states. Because the Americas span much of the ...

journal_title：Epidemics

authors： Lessler J,Dos Santos T,Aguilera X,Brookmeyer R,PAHO Influenza Technical Working Group.,Cummings DAT

更新日期：2010-09-01 00:00:00

abstract：:The past two decades have seen major outbreaks of influenza viruses and flaviviruses that are spread at least in part by migratory birds. Although much new information has accumulated on the natural history of the viruses, and on the geography of migration by individual bird species, no synthesis has been achieved reg...

journal_title：Epidemics

authors： Peterson AT,Andersen MJ,Bodbyl-Roels S,Hosner P,Nyári A,Oliveros C,Papeş M

更新日期：2009-12-01 00:00:00

abstract：:Rapidly evolving pathogens present a major conceptual and mathematical challenge to our understanding of disease dynamics. For these pathogens, the simulation of disease dynamics requires the use of computational models that incorporate pathogen evolution. Currently, these models are limited by two factors. First, the...

journal_title：Epidemics

authors： Koelle K,Kamradt M,Pascual M

更新日期：2009-06-01 00:00:00

abstract：:Detailed results on the dynamics of cowpox virus infection in four natural populations of the field vole, Microtus agrestis, are presented. Populations were sampled every 4 weeks (8 weeks in mid-winter) for 6 years. The purpose was to examine the relationships between overall or susceptible host abundance (N, S) and b...

journal_title：Epidemics

authors： Begon M,Telfer S,Burthe S,Lambin X,Smith MJ,Paterson S

更新日期：2009-03-01 00:00:00